Kyebando is bordered by Kawempe to the northwest, Kikaaya to the northeast, Bukoto to the east, Mulago to the south, Bwaise to the southwest and Kaleerwe to the west. This location lies approximately 5.5 kilometres (3.4 mi), by road, northeast of Kampala's central business district.


The area is located on a hill. The base of the hill is a ring road, Kyebando Ring Road that makes a near-complete circle through the neighborhood. The hill and surrounding area is dotted with school, interspersed with middle-class residential houses


Brimax Pub, Shinners Pub, Diana's Pub, Trend swimming center, and Centenary Car Park are some of the public amenities in the area.


The area has many schools and they include; Kampala Model Primary School - A mixed, non-residential elementary school, St.Stephen Day & Boarding Primary School - A private, mixed, day and residential elementary school, City View College - A private, mixed, non-residential secondary school, City Side College Makerere - Another private secondary college and Millennium College School, among others.